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Nanoparticles as carriers of photosensitizers to improve photodynamic therapy in cancer.

Duy Hieu TruongPhuong Thi Thu TranTuan Hiep Tran
Published in: Pharmaceutical development and technology (2024)
Photodynamic therapy (PDT) has emerged as a promising non-invasive therapeutic approach for cancer treatment, offering unique advantages over conventional treatments. The combination of light activation and photosensitizing agents allows for targeted and localized destruction of cancer cells, reducing damage to surrounding healthy tissues. In recent years, the integration of nanoparticles with PDT has garnered significant attention due to their potential to enhance therapeutic outcomes. This review article aims to provide a comprehensive overview of the current state-of-the-art in utilizing nanoparticles for photodynamic therapy in cancer treatment. We summarized various nanoparticle-based approaches, their properties, and their implications in optimizing PDT efficacy and discussed challenges and future prospects in the field.
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