Syntaxin6 contributes to hepatocellular carcinoma tumorigenesis via enhancing STAT3 phosphorylation.

Li HuangXiaoting ZhongAn LiFuping TuMiao HeXueming XuXiaohui LiuXiaoli ZengJun ChiTian TianChunli WangXiangcai Wang Jianming Ye

Published in: Cancer cell international (2024)

This study provided a novel concept that STX6 exerted oncogenic effects by activating the STAT3 signaling pathway, and STX6 might be a promising therapeutic target for HCC.

Keyphrases

signaling pathway
cell proliferation
pi k akt
epithelial mesenchymal transition
transcription factor
induced apoptosis
protein kinase
oxidative stress