Convenient Synthesis of Functionalized Cyclopropa[c]coumarin-1a-carboxylates.
Olga A IvanovaVladimir A AndronovIrina I LevinaAlexey O ChagarovskiyLeonid G VoskressenskyIgor V TrushkovPublished in: Molecules (Basel, Switzerland) (2018)
A simple method has been developed for the synthesis of cyclopropa[c]coumarins, which belong to the donor-acceptor cyclopropane family and, therefore, are promising substrates for the preparation of chromene-based fine chemicals. The method, based on the acetic acid-induced intramolecular transesterification of 2-arylcyclopropane-1,1-dicarboxylates, was found to be efficient for substrates containing hydroxy group directly attached to the aromatic ring.