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miR-203 inhibits cell proliferation and ERK pathway in prostate cancer by targeting IRS-1.

Yang MengXiaoyan HuShasha LiXinyi ZengLei QiuMingtian WeiZiqing WangJunhong Han
Published in: BMC cancer (2020)
Our results show a novel link between miR-203 and IRS-1, and reveal the importance of strict control of IRS - 1 by miR-203 in the progression of PCa, suggesting miR-203 may act as a promising target for the diagnosis and treatment of advanced PCa.
Keyphrases
  • cell proliferation
  • long non coding rna
  • prostate cancer
  • long noncoding rna
  • cell cycle
  • radical prostatectomy
  • genome wide
  • dna methylation
  • single cell