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Clinicopathologic and Molecular Analysis of Normal Karyotype Therapy-Related and De Novo Acute Myeloid Leukemia: A Multi-Institutional Study by the Bone Marrow Pathology Group.

Miguel Dario CantuRashmi Kanagal-ShamanaSa A WangTapan Mahendra KadiaCarlos E Bueso-RamosSanjay S PatelJulia T GeyerWayne TamYazan F MadanatPeng LiTracy I GeorgeMeredith M NicholsHeesun Joyce RogersYen-Chun LiuNidhi AggarwalJason H KurzerDanielle L V MaracajaEric D HsiFeras ZaiemDaniel BabuKathryn FoucarDorottya LaczkoAdam BaggAttilio OraziDaniel A ArberRobert P HasserjianOlga K Weinberg
Published in: JCO precision oncology (2023)
To our knowledge, this is the largest study to date to comprehensively evaluate NK-t-AML and provides a framework that may inform our understanding of NK-t-AML disease biology and could potentially help guide therapeutic management and improved disease classification in t-MNs that lack cytogenetic aberrations.
Keyphrases
  • acute myeloid leukemia
  • bone marrow
  • healthcare
  • allogeneic hematopoietic stem cell transplantation
  • machine learning
  • mesenchymal stem cells
  • stem cells
  • genome wide