MRI-derived radiomics assessing tumor-infiltrating macrophages enable prediction of immune-phenotype, immunotherapy response and survival in glioma.
Di ChenRui ZhangXiaoming HuangChunxia JiWei XiaYing QiXinyu YangLishuang LinJing WangHaixia ChengWeijun TangJinhua YuDave S B HoonJun ZhangXin GaoYu YaoPublished in: Biomarker research (2024)
The radiomic model could allow for non-invasive assessment of the absolute density of TAM from MRI images in HGG patients. Of note, our RIB model is the first immunological radiomic model confirmed to have the ability to predict survival benefits from DC vaccine in gliomas, thereby providing a novel tool to inform treatment decisions and monitor patient treatment course by radiomics.
Keyphrases
- contrast enhanced
- magnetic resonance imaging
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- computed tomography
- deep learning
- magnetic resonance
- case report
- dendritic cells
- prognostic factors
- high grade
- immune response
- squamous cell carcinoma
- convolutional neural network
- free survival
- optical coherence tomography
- patient reported outcomes
- peritoneal dialysis
- clinical evaluation