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Effects of repeated oral doses of ketoconazole on a sequential ascending single oral dose of fedratinib in healthy subjects.

Ken OgasawaraChristine XuVanaja KanamaluruMaria PalmisanoGopal Krishna
Published in: Cancer chemotherapy and pharmacology (2020)
These results serve as the basis for fedratinib dose reduction when fedratinib is coadministered with strong CYP3A4 inhibitors.
Keyphrases
  • pulmonary artery
  • coronary artery
  • aortic dissection