Rational development of synergistic combinations of chemotherapy and molecular targeted agents for colorectal cancer treatment.

Diego TosiEsther Pérez-GraciaSalima AtisNadia ViéEve CombèsMélissa GabanouChristel LarbouretMarta JarlierCaroline MolleviAdeline TorroMaguy Del RioPierre MartineauCéline Gongora

Published in: BMC cancer (2018)

Analysis of chemotherapy-induced phosphokinome changes helps to elucidate the mechanisms of drug resistance and to guide the selection of targets for combination therapies with synergistic activity.

Keyphrases

chemotherapy induced
cancer therapy
drug delivery
combination therapy
squamous cell carcinoma
single molecule
replacement therapy
rectal cancer