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rWTC-MBTA: autologous vaccine prevents metastases via antitumor immune responses.

Juan YeHerui WangRogelio MedinaSamik ChakrabortyMitchell SunAlex ValenzuelaXueyu SangYaping ZhangOndrej UherJan ZenkaKarel PacakZhengping Zhuang
Published in: Journal of experimental & clinical cancer research : CR (2023)
The rWTC-MBTA vaccine demonstrated efficacy in multiple animal models through T-cell mediated cytotoxicity and has potential as a therapeutic option for preventing and treating tumor metastasis with minimal systemic toxicity.
Keyphrases
  • immune response
  • oxidative stress
  • bone marrow
  • cell therapy
  • toll like receptor
  • dendritic cells
  • stem cells
  • mouse model
  • risk assessment
  • mesenchymal stem cells
  • inflammatory response