Verrucous carcinoma of the oesophagus is a genetically distinct subtype of oesophageal squamous cell carcinoma.
Raymond A IsidroFei DongJason L HornickJon O WeeAgoston AgostonDeepa T PatilVikram DeshpandeLei ZhaoPublished in: Histopathology (2021)
VSCC is not only morphologically but also genetically distinct from conventional oesophageal SCC, featuring frequent SMARCA4 mutations and infrequent TP53 mutations or CDKN2A/B CNVs. Molecular findings may aid in establishing the challenging diagnosis of VSCC.