Mass Spectrometric Analysis of Cerebrospinal Fluid Ubiquitin in Alzheimer's Disease and Parkinsonian Disorders.

Simon SjödinOskar HanssonAnnika ÖhrfeltGunnar BrinkmalmHenrik ZetterbergAnn BrinkmalmKaj Blennow

Published in: Proteomics. Clinical applications (2017)

CSF ubiquitin may reflect dysfunctional proteostasis in AD. The described method can be used for further exploration of ubiquitin as a potential biomarker in neurodegenerative diseases.

Keyphrases

cerebrospinal fluid
small molecule
cognitive decline