Circulating Adipokines and Associations With Incident Cardiovascular Disease in Rheumatoid Arthritis.
Lydia E FedericoTate M JohnsonBryant R EnglandKatherine D WyshamMichael D GeorgeBrian C SauerBartlett C HamiltonCarlos D HunterMichael J DuryeeGeoffrey M ThieleTed R MikulsJoshua F BakerPublished in: Arthritis care & research (2022)
Adipokines are associated with HF hospitalization and CVD-related death in patients with RA, with stronger associations in nonobese participants. These findings suggest that adipokines effectively predict clinically important outcomes in RA perhaps through an association with body composition and metabolic health. Further study is needed to determine whether adipokine measures might augment existing tools to identify RA patients at increased risk of CVD.
Keyphrases
- rheumatoid arthritis
- body composition
- cardiovascular disease
- disease activity
- ankylosing spondylitis
- resistance training
- interstitial lung disease
- bone mineral density
- public health
- healthcare
- systemic lupus erythematosus
- mental health
- type diabetes
- systemic sclerosis
- metabolic syndrome
- cardiovascular risk factors
- risk assessment
- adipose tissue
- high intensity
- coronary artery disease
- atrial fibrillation
- drug induced