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METTL3 promotes lung adenocarcinoma tumor growth and inhibits ferroptosis by stabilizing SLC7A11 m 6 A modification.

Yiming XuDandan LvChao YanHua SuXue ZhangYangfeng ShiKejing Ying
Published in: Cancer cell international (2022)
These findings reinforced the oncogenic role of METTL3 in LUAD progression and revealed its underlying correlation with cancer cell ferroptosis; these findings also indicate that METTL3 is a promising novel target in LUAD diagnosis and therapy.
Keyphrases
  • cell death
  • transcription factor
  • stem cells
  • cell therapy
  • tissue engineering