Presentation, diagnosis, and management of the Li-Fraumeni syndrome.

Li-Fraumeni syndrome is a hereditary cancer syndrome that results in a dramatically increased risk of developing cancer over a patient's lifetime. Proper understanding of this syndrome is important for physicians across all specialties, as it can result in earlier cancer diagnosis and treatment. Here, we present the case of a patient presenting with Li-Fraumeni syndrome and discuss the appropriate screening recommendations and management of patients with this disorder.