Asymptomatic left ventricular dysfunction in patients with type 2 diabetes free of cardiovascular disease and its relationship with clinical characteristics: The DIACAR cohort study.
Yara Antakly-HanonAdrien Ben HamouPhilippe GarçonYoann MoeufIsabela BanuMaxime FumeryAdela VoicanPhilippe AbassadeConstance OriezGilles ChatellierOlivier DupuyRomain CadorMichel KomajdaPublished in: Diabetes, obesity & metabolism (2020)
A high prevalence of asymptomatic cardiac dysfunction/structural abnormalities was observed in patients with T2DM without overt cardiac disease and was associated with either age, diabetes duration or treatment and with comorbidities including hypertension and obesity. Whether these preclinical abnormalities are associated with poor outcomes warrants further study.
Keyphrases
- left ventricular
- cardiovascular disease
- type diabetes
- glycemic control
- blood pressure
- oxidative stress
- hypertrophic cardiomyopathy
- insulin resistance
- heart failure
- metabolic syndrome
- acute myocardial infarction
- cardiac resynchronization therapy
- weight loss
- mitral valve
- left atrial
- weight gain
- cell therapy
- skeletal muscle
- adipose tissue
- physical activity
- coronary artery disease
- combination therapy
- mesenchymal stem cells
- bone marrow
- transcatheter aortic valve replacement
- replacement therapy
- arterial hypertension