Immune Responses Induced by mRNA Vaccination in Mice, Monkeys and Humans.

Published in: Vaccines (2021)

In this concise review, we summarize the concepts behind mRNA vaccination. We discuss the innate and adaptive immune response generated by mRNA vaccines in different animal models and in humans. We give examples of viral infections where mRNA vaccines have shown to induce potent responses and we discuss in more detail the recent SARS-CoV-2 mRNA vaccine trials in humans.

Keyphrases

immune response
sars cov
binding protein
dendritic cells
toll like receptor
metabolic syndrome
insulin resistance
coronavirus disease
respiratory syndrome coronavirus
high fat diet induced