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APOE genotype moderates the relationship between LRP1 polymorphism and cognition across the Alzheimer's disease spectrum via disturbing default mode network.

Feifei ZangYao ZhuQianqian ZhangChang TanQing WangChun-Ming Xienull null
Published in: CNS neuroscience & therapeutics (2021)
These findings suggested LRP1 could affect DMN and provided a stage-dependent neuroimaging biomarker for classifying AD spectrum populations.
Keyphrases
  • cognitive decline
  • mild cognitive impairment
  • functional connectivity
  • low density lipoprotein
  • genetic diversity