Perampanel's forgiveness factor in a variable medication adherence paradigm in a rat model of chronic epilepsy.

Michelle GuignetAmanda CampbellJonathan VuongDale WhittingtonH Steve White

Published in: Journal of translational medicine (2023)

If our preclinical data is supported in the clinic, PER's favorable pharmacokinetic profile in humans, combined with a lowered risk of breakthrough seizures suggests that it may provide a certain forgiveness factor if a dose is missed within a 24-h window.

Keyphrases

primary care
electronic health record
big data
cell therapy
temporal lobe epilepsy
stem cells
deep learning
drug induced