A non-invasive 25-Gene PLNM-Score urine test for detection of prostate cancer pelvic lymph node metastasis.

Jinan GuoLiangyou GuHeather JohnsonDi GuZhenquan LuBinfeng LuoQian YuanXuhui ZhangTaolin XiaQingsong ZengAlan H B WuAllan JohnsonNishtman DizeyiPer-Anders AbrahamssonHeqiu ZhangLingwu ChenKefeng XiaoChang ZouJenny L Persson

Published in: Prostate cancer and prostatic diseases (2024)

The novel 25 G PLNM-Score is the first highly accurate and non-invasive machine learning algorithm-based urine test to identify PLNM before PLND, with potential clinical benefits of avoiding unnecessary PLND and improving treatment decision-making.

Keyphrases

lymph node metastasis
machine learning
prostate cancer
decision making
squamous cell carcinoma
papillary thyroid
deep learning
artificial intelligence
radical prostatectomy
genome wide
copy number
rectal cancer
high resolution
gene expression
label free
transcription factor
risk assessment