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Serum proteomics profiling identifies a preliminary signature for the diagnosis of early-stage lung cancer.

Roberto GasparriRoberta NoberiniAlessandro CuomoAvinash YadavDavide TricaricoCarola SalvettoPatrick MaisonneuveValentina CaminitiGiulia SeddaAngela SabalicTiziana BonaldiLorenzo Spaggiari
Published in: Proteomics. Clinical applications (2023)
Our study identified a preliminary, non-invasive protein signature able to discriminate with high specificity and selectivity early-stage lung cancer patients from high-risk healthy subjects. These results provide the basis for future validation studies for the development of a non-invasive diagnostic tool for lung cancer.
Keyphrases
  • early stage
  • sentinel lymph node
  • mass spectrometry
  • genome wide
  • current status
  • structural basis
  • protein protein
  • gene expression
  • amino acid
  • case control
  • lymph node
  • rectal cancer