Clinical Significance of Upper Airway Virus Detection in Critically Ill Hematology Patients.
Jérôme Le GoffNoémie ZucmanVirginie LemialeDjamel MokartFrédéric PèneJérôme LambertAchille KouatchetAlexandre DemouleFrançois VincentMartine NyungaFabrice BruneelAdrien ContejeanSéverine Mercier-DelarueAntoine RabbatChristine LebertPierre PerezAnne-Pascale MeertDominique BenoitCarole SchwebelMercé JourdainMichael DarmonMatthieu Resche-RigonElie AzoulayPublished in: American journal of respiratory and critical care medicine (2020)
Respiratory virus detection in the upper airway by multiplex PCR assay is common in critically ill hematology patients. In patients with ARF, respiratory virus detection was independently associated with ICU mortality. Multiplex PCR assay may prove helpful for the risk stratification of hematology patients with ARF. Studies to understand whether respiratory tract viruses play a causal role in outcomes are warranted.