Changes in Brain Activation Pattern During Working Memory Tasks in People With Post-COVID Condition and Persistent Neuropsychiatric Symptoms.

Linda ChangMeghann C RyanHua-Jun LiangXin ZhangEric CunninghamJustin WangEleanor WilsonEdward H HerskovitsShyamasundaran KottililThomas M Ernst

Published in: Neurology (2023)

PCC participants with neuropsychiatric symptoms demonstrated compensatory neural processes with greater usage of alternate brain regions, and reorganized networks, to maintain normal performance during WM tasks. BOLD-fMRI was sensitive for detecting brain abnormalities that correlated with various quantitative neuropsychiatric symptoms.

Keyphrases

working memory
resting state
functional connectivity
white matter
transcranial direct current stimulation
attention deficit hyperactivity disorder
coronavirus disease
sars cov
sleep quality
cerebral ischemia
brain injury
blood brain barrier
depressive symptoms