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Identification of aberrantly methylated differentially expressed genes in breast cancer by integrated bioinformatics analysis.

Lilan YiPeng LuoJian Zhang
Published in: Journal of cellular biochemistry (2019)
Our study reveals possible methylation-based DEGs and involved pathways in breast cancer, which could provide novel insights into underlying pathogenesis mechanisms. Abnormally methylated oncogenes and TSGs, especially ATM and DICER1, may emerge as novel biomarkers and therapeutic targets for breast cancer in the future.
Keyphrases
  • bioinformatics analysis
  • genome wide
  • dna methylation
  • breast cancer risk
  • young adults
  • childhood cancer
  • genome wide analysis