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Variation in lung function and alterations in cardiac structure and function-Analysis of the UK Biobank cardiovascular magnetic resonance imaging substudy.

Ross J ThomsonNay AungMihir M SanghviJose Miguel PaivaAaron M LeeFilip ZemrakKenneth FungPaul E PfefferAlexander J MackayTricia M McKeeverElena LukaschukValentina CarapellaYoung Jin KimCharlotte E BoltonStefan K PiechnikStefan NeubauerSteffen E Petersen
Published in: PloS one (2018)
This study shows that reduced FEV1 and FVC are associated with smaller ventricular volumes and reduced ventricular mass. The changes seen per standard deviation change in FEV1 and FVC are comparable to one decade of ageing.
Keyphrases
  • lung function
  • left ventricular
  • magnetic resonance imaging
  • heart failure
  • cystic fibrosis
  • chronic obstructive pulmonary disease
  • air pollution
  • catheter ablation
  • computed tomography
  • atrial fibrillation