FOXC1 and FOXC2 Ablation Causes Abnormal Valvular Endothelial Cell Junctions and Lymphatic Vessel Formation in Myxomatous Mitral Valve Degeneration.

Can Tan Zhi-Dong Ge Shreya Kurup Yaryna Dyakiv Ting Liu William A Muller Tsutomu Kume

Published in: Arteriosclerosis, thrombosis, and vascular biology (2024)

are required for maintaining the integrity of the MV, including VEC junctions, ECM organization, and lymphatic vessel formation/function to prevent myxomatous MV degeneration.

Keyphrases

mitral valve
lymph node
single molecule
endothelial cells
atrial fibrillation
left atrial
left ventricular
extracellular matrix