TNFR1 signaling is positively regulated by Jak-2 and c-Src via tyrosine phosphorylation.

Published in: Turkish journal of biology = Turk biyoloji dergisi (2023)

TNFR1 is tyrosine phosphorylated by both c-Src and JAK2, triggering a "noncanonical" pathway, that activates ERK and Akt.

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