Compromised Volumetric Bone Density and Microarchitecture in Men With Congenital Hypogonadotropic Hypogonadism.
Agnès OstertagGeorgios E PapadakisCorinne ColletSeverine TrabadoLuigi MaioneNelly PitteloudJerome BouligandMarie Christine De VernejoulMartine Cohen-SolalJacques YoungPublished in: The Journal of clinical endocrinology and metabolism (2021)
Both vBMD and bone microarchitecture remain impaired in CHH/KS men despite long-term hormonal treatment. Treatment initiation during adolescence is associated with enhanced trabecular outcomes, highlighting the importance of early diagnosis.