Risk Assessment of Nine Coccidiostats in Commercial and Home Raised Poultry.
Rui R MartinsVanessa S AzevedoAndré M P T PereiraLiliana J G SilvaSofia C DuarteAngelina PenaPublished in: Journal of agricultural and food chemistry (2021)
For the first time, this paper aimed to evaluate nine ionophore and synthetic coccidiostat residues in poultry muscle samples, obtained from different production types, by solid-liquid extraction followed by liquid chromatography with tandem mass spectrometry (LC-MS/MS). The fully validated methodology was successfully applied to a total of 101 chicken and turkey samples obtained from canteens, supermarkets, and home productions in Portugal. Halofuginone, diclazuril, decoquinate, narasin, lasalocid, and salinomycin were detected in 20.8% of the samples. Home raised samples showed a greater frequency, 47.1%. The synthetic coccidiostats halofuginone, diclazuril, and decoquinate were found in averages of 0.7 μg kg-1,2.9 μg kg-1, and 3.7 μg kg-1, respectively, while averages of 1.2 μg kg-1, 1.6 μg kg-1, and 1.3 μg kg-1 were found regarding the ionophores narasin, lasalocid, and salinomycin. As for the risk assessment, values lower than 8.06% of the acceptable daily intake (ADI) were observed, indicating that exposure to coccidiostats through consumption of poultry meat does not represent risk to consumers.
Keyphrases
- tandem mass spectrometry
- liquid chromatography
- risk assessment
- ultra high performance liquid chromatography
- healthcare
- mass spectrometry
- high performance liquid chromatography
- high resolution mass spectrometry
- gas chromatography
- human health
- heavy metals
- antimicrobial resistance
- skeletal muscle
- physical activity
- cancer stem cells
- climate change