A novel nitroalkene-α-tocopherol analogue inhibits inflammation and ameliorates atherosclerosis in Apo E knockout mice.

Jorge Rodriguez-DuarteGermán GalliussiRosina DapuetoJessica RosselloLeonel MalacridaAndrés KamaidFrancisco J SchopferCarlos EscandeGloria V LópezCarlos Batthyany

Published in: British journal of pharmacology (2019)

In toto, the data demonstrate a novel pharmacological strategy for the prevention of atherosclerosis based on a creative, natural and safe drug delivery system of a non-conventional anti-inflammatory compound (NATOH) with significant potential for clinical application.

Keyphrases

anti inflammatory
cardiovascular disease
oxidative stress
electronic health record
big data
type diabetes
deep learning
data analysis