α 1 -Adrenoceptors activate the NLRP3 inflammasome through downregulation of Kir2.1 in cardiac inflammation.
Ling ChenWenbo WangXiangyang PengLuqian LiuAimei ZhangXinzhi LiKe-Tao MaLi Wang
Published in: Experimental physiology (2022)
-AR overactivation, which induces cardiac inflammation, through the NF-κB signalling pathway, and activating Kir2.1 can downregulate NLRP3 inflammation and exert cardioprotective effects induced by zacopride.