MicroRNAs as Potential Liquid Biopsy Biomarker for Patients with Castration-Resistant Prostate Cancer.
Nicolas FernandezJulian ChavarriagaPaola AyalaAdriana Marcela Pedraza-BermeoJohn BolivarJuan Guillermo PradaJuan Guillermo CatañoHerney Andres García-PerdomoJuliana VillanuevaDaniela VarelaIgnacio ZarantePublished in: Research and reports in urology (2022)
We explored the miRNA expression profile in patients with CRPC, identifying five miRNAs implicated in the regulation of genes involved in prostate cancer (PCa) oncogenesis and progression. We also found miRNA 855-3p in peripheral blood for the first time, which has a critical role in tumor growth mechanisms and higher expression profile than in healthy individuals.