Adaptive physiological water conservation explains hypertension and muscle catabolism in experimental chronic renal failure.
Johannes J KovarikNorihiko MorisawaJohannes WildAdriana MartonKaoru Takase-MinegishiShintaro MinegishiSteffen DaubJeff M SandsJanet D KleinJames L BaileyJean-Paul KovalikManfred RauhSusanne KarbachKarl F HilgersFriedrich C LuftAkira NishiyamaDaisuke NakanoKento KitadaJens M TitzePublished in: Acta physiologica (Oxford, England) (2021)
Physiological adaptation to body water loss, termed aestivation, is an evolutionary conserved survival strategy and an under-studied research area in medical physiology, which besides hypertension and muscle mass loss in chronic renal failure may explain many otherwise unexplainable phenomena in medicine.
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