Advanced glycation end products correlate with breast cancer metastasis by activating RAGE/TLR4 signaling.

Shuo PanYitong GuanYanpeng MaQianwei CuiZhiguo TangJingyuan LiChao ZuYong ZhangLing ZhuJie JiangZhongwei Liu

Published in: BMJ open diabetes research & care (2022)

AGEs are correlated with metastasis of breast cancer. AGEs' promoting effects on migration and invasion of breast cancer cells via activating RAGE/TLR4/MyD88 signaling were suggested as the involved mechanism.

Keyphrases

toll like receptor
breast cancer cells
inflammatory response
signaling pathway
immune response
nuclear factor
young adults
breast cancer risk