Possible Common Aetiology behind Maternal Preeclampsia and Congenital Heart Defects in the Child: a Cardiovascular Diseases in Norway Project Study.

Kristoffer BrodwallElisabeth LeirgulGottfried GreveStein Emil VollsetHenrik HolmstrømGrethe S TellNina Øyen

Published in: Paediatric and perinatal epidemiology (2015)

Early-onset preeclampsia was strongly associated with infant risk of severe CHD, specifically; the risk of AVSD was 15-fold higher if the mother was diagnosed with early-onset preeclampsia, suggesting common aetiological factors for early-onset preeclampsia and erroneous fetal heart development.

Keyphrases

early onset
late onset
cardiovascular disease
heart failure
birth weight
pregnancy outcomes
weight loss
body mass index
drug induced