Uric acid predicts long-term cardiovascular risk in type 2 diabetes but does not mediate the benefits of fenofibrate: The FIELD study.

Jacob Y CaoBoris WaldmanRachel O'ConnellDavid R SullivanRussell S ScottNanda AryalVal GebskiIan MarschnerMarja-Riitta TaskinenJohn R SimesNeil McGillAlicia J JenkinsAnthony C Keechnull null

Published in: Diabetes, obesity & metabolism (2020)

UA is a strong independent predictor of long-term cardiovascular risk in adults with T2D. Although greater reduction in UA on fenofibrate is predictive of lower cardiovascular risk, this does not appear to mediate the cardioprotective effects of fenofibrate.

Keyphrases

uric acid
type diabetes
metabolic syndrome
insulin resistance
glycemic control