Notch Signaling Promotes Mature T-Cell Lymphomagenesis.

Xin Gao Chenguang Wang Suhaib Abdelrahman Nermin Kady Carlos A Murga-Zamalloa Peter H Gann Maria Sverdlov Ashley Wolfe Avery Polk Noah A Brown Nathanael Glen Bailey Kedar Inamdar Sandro Casavilca Jaime Montes Carlos Barrionuevo Luis Taxa John C Reneau Christian W Siebel Ivan P Maillard Ryan A Wilcox

Published in: Cancer research (2022)

This work demonstrates that ligand-dependent Notch activation promotes the growth and proliferation of mature T-cell lymphomas, providing new therapeutic strategies for this group of aggressive lymphomas.

Keyphrases

signaling pathway