Lipidomic profiling of extracellular vesicles derived from prostate and prostate cancer cell lines.
Joshua S BrzozowskiHelen JankowskiDanielle R BondSiobhan B McCagueBenjamin R MunroMelanie J PredebonChristopher J ScarlettKathryn A SkeldingJudith WeidenhoferPublished in: Lipids in health and disease (2018)
This study identified differences in the molecular lipid species of prostate cell-derived EVs, increasing our understanding of the changes that occur to the EV lipidome during prostate cancer progression. These differences highlight the importance of characterising the EV lipidome, which may lead to improved diagnostic and prognostic biomarkers for prostate cancer.