Revisiting the Effect of Leptin on Alzheimer Disease and Parkinson Disease: The Role of Insulin Sensitivity.
Xingzhi GuoPeng TangXin ZhangRui LiPublished in: The Journal of clinical endocrinology and metabolism (2024)
The study offers evidence supporting a potential protective effect of leptin in AD, but not PD, via the enhancement of insulin sensitivity. Our findings underscore the distinct roles of leptin in AD and PD.