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Mouse Cardiovascular Imaging.

Colin K L PhoonOrlando AristizábalMohammed FarhoudDaniel H TurnbullYoussef Z Wadghiri
Published in: Current protocols (2024)
The mouse is the mammalian model of choice for investigating cardiovascular biology, given our ability to manipulate it by genetic, pharmacologic, mechanical, and environmental means. Imaging is an important approach to phenotyping both function and structure of cardiac and vascular components. This review details commonly used imaging approaches, with a focus on echocardiography and magnetic resonance imaging, with brief overviews of other imaging modalities. In this update, we also emphasize the importance of rigor and reproducibility in imaging approaches, experimental design, and documentation. Finally, we briefly outline emerging imaging approaches but caution that reliability and validity data may be lacking. © 2024 Wiley Periodicals LLC.
Keyphrases
  • high resolution
  • magnetic resonance imaging
  • left ventricular
  • gene expression
  • mass spectrometry
  • pulmonary hypertension
  • big data
  • copy number
  • climate change
  • deep learning
  • contrast enhanced