Antiretroviral therapy and HIV-associated cardiovascular disease: a prospective cardiac biomarker and CMR tissue characterization study.
Pieter-Paul S RobbertseAnton F DoubellTonya M EsterhuizenPhilip G HerbstPublished in: ESC heart failure (2023)
Our cardiac biomarker data support the presence of subclinical myocardial injury, remodelling, and fibrosis at HIV diagnosis, and ART had a positive influence on these blood markers. It remains unclear if the underlying pathological processes were fully addressed by ART. The ability of cardiac biomarkers to detect and track tissue abnormalities diagnosed with CMR showed promise. With additional research, this could lead to improvements in screening and monitoring myocardial abnormalities, even in CMR-limited settings.
Keyphrases
- antiretroviral therapy
- hiv infected
- hiv positive
- human immunodeficiency virus
- hiv infected patients
- hiv aids
- left ventricular
- cardiovascular disease
- big data
- hiv testing
- type diabetes
- men who have sex with men
- hepatitis c virus
- electronic health record
- metabolic syndrome
- south africa
- heart failure
- cardiovascular risk factors
- data analysis