Combining molecular testing and the Bethesda category III:VI ratio for thyroid fine-needle aspirates: A quality-assurance metric for evaluating diagnostic performance in a cytopathology laboratory.
Hamza Numan GokozanThomas L DilcherSusan A AlpersteinYuqing QiuMaria MostykaTheresa ScognamiglioJames P SolomonWei SongHanna RennertShaham BegEvan SternAbha GoyalMomin T SiddiquiJonas J HeymannPublished in: Cancer cytopathology (2021)
Lack of correlation between the NGA rate and easily calculable diagnostic ratios enables the calibration of diagnostic thresholds, even for CPs who have normal metrics. Specifically, calculation of the NGA rate and the III:VI ratio may allow individual CPs to determine whether they are overcalling or undercalling cases that other CPs might otherwise recategorize.