COVID-19 Severity and Stroke: Correlation of Imaging and Laboratory Markers.

Jeffrey M Katz R B Libman Jason J Wang Christopher G Filippi Pina C Sanelli Avraham Zlochower Michele Gribko S V Pacia Ruben Kuzniecky Souhel Najjar S Azhar

Published in: AJNR. American journal of neuroradiology (2020)

Patients with stroke hospitalized with severe COVID-19 are characterized by higher inflammatory, coagulopathy, and tissue-damage biomarkers, supporting proposed pathogenic mechanisms of hyperinflammation activating a prothrombotic state. Cautious balancing of thrombosis and the risk of hemorrhagic transformation is warranted when considering anticoagulation.

Keyphrases

atrial fibrillation
coronavirus disease
sars cov
oxidative stress
signaling pathway
pulmonary embolism
venous thromboembolism
early onset
respiratory syndrome coronavirus
cerebral ischemia
drug induced
fluorescence imaging
blood brain barrier