Prolonged Opioid Use and Pain Outcome And Associated Factors after Surgery Under General Anesthesia: A Prospective Cohort Association Multicenter Study.
Kai KuckBhiken I NaikKaren B DominoKaren L PosnerLeif SaagerAmi R StuartKen B JohnsonSalome B AlpertMarcel E DurieuxAnik K SinhaChad M BrummettMichael F AzizKenneth C Cummings IiiJohn G GaudetAndrea KurzMienke RijsdijkJonathan P WandererNathan L PacePublished in: Anesthesiology (2023)
Preoperative opioid use was the strongest predictor of opioid use three months post surgery. None of the other variables showed clinically significant association with opioid use at three months after surgery.