Mast cells are increased in the small intestinal mucosa of patients with irritable bowel syndrome: A systematic review and meta-analysis.
Alejandro RoblesDavid Perez InglesKanchana MyneeduAbhizith DeokerIrene SarosiekMarc J ZuckermanMax J SchmulsonMohammad BashashatiPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2019)
Mast cells are increased in the small intestine of IBS vs controls, mainly in the ileum. Future studies should address whether such findings are IBS subtype or gender-dependent. Methodological variations, single-center bias, and the limited number of studies included in this meta-analysis may affect the final results.