Design of experiments for fine-mapping quantitative trait loci in livestock populations.
Dörte WittenburgSarah BonkMichael DoschorisHenry ReyerPublished in: BMC genetics (2020)
Our approach incorporates information about the population structure into the design of experiments. Compared to a conventional method, this leads to a reduced estimate of sample size enabling the resource-saving design of future experiments for fine-mapping of candidate variants.