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Comprehensive Genomic Profiling of High-Risk Pediatric Cancer Patients Has a Measurable Impact on Clinical Care.

Ryan J SummersSharon M CastellinoChristopher C PorterTobey J MacDonaldGargi D BasuSzabolcs SzelingerManoj K BhasinThomas CashAlexis B CarterRobert Craig CastellinoJason R FangusaroSarah G MitchellMelinda G PaulyBojana PenchevaDaniel S WechslerDouglas K GrahamKelly C Goldsmith
Published in: JCO precision oncology (2022)
Paired tumor/normal whole-exome sequencing and tumor RNA Seq of de novo or relapsed/refractory tumors was feasible and clinically impactful in high-risk pediatric cancer patients.
Keyphrases
  • rna seq
  • single cell
  • healthcare
  • acute lymphoblastic leukemia
  • palliative care
  • diffuse large b cell lymphoma
  • multiple myeloma
  • quality improvement
  • hodgkin lymphoma
  • copy number
  • gene expression
  • genome wide