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Admission Dehydration Status Portends Adverse Short-Term Mortality in Patients with Spontaneous Intracerebral Hemorrhage.

Felix LehmannLorena M SchenkJoshua D BernstockChristian BodeValeri BorgerFlorian A GesslerErdem GüresirMotaz HamedAnna-Laura PotthoffChristian PutensenMatthias SchneiderJulian ZimmermannHartmut VatterPatrick SchussAlexis Hadjiathanasiou
Published in: Journal of clinical medicine (2021)
The impact of dehydration at admission of patients with spontaneous intracerebral hemorrhage (ICH) on short-term mortality remains ambiguous due to scarce data. All of the consecutive patients with spontaneous ICH, who were referred to our neurovascular center in 2018/19, were assessed for hydration status on admission. Dehydration was defined by a blood urea-to-creatinine ratio > 80. In a cohort of 249 patients, 76 patients (31%) were dehydrated at the time of admission. The following factors were significantly and independently associated with increased 30-day mortality in multivariate analysis: "signs of cerebral herniation" ( p = 0.008), "initial midline shift > 5 mm" ( p < 0.001), "ICH score > 3" ( p = 0.007), and "admission dehydration status" ( p = 0.007). The results of the present study suggest that an admission dehydration status might constitute a significant and independent predictor of short-term mortality in patients with spontaneous ICH.
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