Evaluation of the impact of CSF prion RT-QuIC and amended criteria on the clinical diagnosis of Creutzfeldt-Jakob disease: a 10-year study in Italy.

Andrea MastrangeloAngela MammanaSimone BaiardiDorina TipleElisa ColaizzoMarcello RossiLuana VaianellaBarbara PolischiMichele EquestreAnna PoleggiSabina CapellariAnna LadoganaPiero Parchi

Published in: Journal of neurology, neurosurgery, and psychiatry (2022)

CSF RT-QuIC is highly sensitive and specific for diagnosing CJD in vitam. The Q-CM criteria provide a high diagnostic value for CJD.

Keyphrases

risk assessment
mass spectrometry
high resolution
single molecule