VRAM Flap for Pelvic Floor Reconstruction after Pelvic Exenteration and Abdominoperineal Excision.
Ionut Flaviu FaurAdelina ClimAmadeus DobrescuCatalin Prodan-BarbulescuRami HajjarPaul PascaMarco CapitanioCristi TartaAlexandru IsaicGeorge NoditiIonel Daniel NatiBogdan TotoliciCiprian DutaGabriel LazarPublished in: Journal of personalized medicine (2023)
Due to the still large number of patients diagnosed with pelvic neoplasms (colorectal, gynecological, and urological) in advanced stages right from the initial diagnosis, surgery represents the mainstay of treatment, often implying wide, eventually multi-organ resections in order to achieve negative surgical margins. Perineal wound morbidity, particularly in extralevator abominoperineal excision, leads to complications and local infection rates of up to 40%. Strategies to reduce postoperative wound complications are being pursued to address this issue. The VRAM flap remains the gold standard for autologous reconstruction after pelvic oncological resection; it was initially designed for abdominal wall defects and later expanded for large pelvic tissue defects. The flap's application is based on its physical characteristics, including abundant tissue and a generous skin paddle, which effectively obliterates dead space after exenterations. The generous skin paddle offers good cosmetic and functional outcomes at the recipient site. This article describes the case of a patient histopathologically diagnosed with stage IIIA squamous cell carcinoma of the uterine cervix who received multimodal onco-surgical treatment. The surgical mainstay of this treatment is pelvic exenteration. Pelvic reconstruction after this major surgery was performed using a vertical flap with the rectus abdominis.
Keyphrases
- rectal cancer
- soft tissue
- locally advanced
- squamous cell carcinoma
- minimally invasive
- end stage renal disease
- breast reconstruction
- coronary artery bypass
- wound healing
- prostate cancer
- mental health
- bone marrow
- coronary artery disease
- chronic kidney disease
- case report
- peritoneal dialysis
- radiation therapy
- acute coronary syndrome
- prognostic factors
- stem cells
- lymph node metastasis
- atrial fibrillation
- preterm birth
- mesenchymal stem cells
- robot assisted
- radical prostatectomy