Evaluation of a new technique using artificial intelligence for quantification of plasma cells on CD138 immunohistochemistry.

Ethan James GantanaErica-Mari NellErnest MusekwaRobert Kingsley LohlunCarissa ChettyKeshanya MoodleySylvester ChabunyaJacqui RasZivanai Cuthbert Chapanduka

Published in: International journal of laboratory hematology (2023)

We were able to successfully count CD138-positive plasma cells in bone marrow biopsies using artificial intelligence. This method is superior to both manual counting and overview estimation, regardless of tumour load.

Keyphrases

artificial intelligence
machine learning
big data
induced apoptosis
deep learning
bone marrow
cell cycle arrest
mesenchymal stem cells
endoplasmic reticulum stress
signaling pathway
peripheral blood
nk cells